Vitamins are a class of trace, low-molecular-weight organic compounds essential for maintaining the body’s life processes. They are diverse in type and have different chemical structures. Physiologically, they are neither the main raw materials for the formation of various tissues nor the source of energy in the body, but they play an important role in the body’s metabolism of substances and energy. This article will provide an in-depth understanding of the functions of vitamin B12, deficiency symptoms, and recommended intake.
What is vitamin B12?
Vitamin B12, also known as cobalamin, is a vitamin containing a metallic element that is essential for human health. It plays a crucial role in red blood cell production, nervous system health, and DNA synthesis.
Why are more and more elderly people deficient in B12?
Decreased absorption capacity is the main cause.
Older adults experience reduced gastric acid secretion, making it difficult for B12 from food to be released. A survey published in the *Chinese Journal of Clinical Nutrition* indicated that approximately 18% of people over 60 years of age have B12 deficiency. Some people are not “eating less,” but rather “not absorbing enough.”
Changes in dietary structure
Many elderly people, in pursuit of a “light and healthy diet,” almost completely avoid meat, eggs, and dairy products. However, vitamin B12 is almost exclusively found in animal-based foodsâover time, this can easily lead to a deficiency.
Medications “steal” vitamins
People who take stomach medications or hypoglycemic drugs (such as metformin) for a long time will experience a significant decrease in their B12 levels. Nutrition experts at Peking Union Medical College Hospital point out that elderly people who take these medications long-term have approximately twice the risk of B12 deficiency.

You may have signs of vitamin B12 deficiency
extreme fatigue or weakness
Pale skin (suggesting severe anemia)
Rapid breathing (especially noticeable when getting up)
Tingling or numbness in the hands and feet, or electric shock-like neuralgia throughout the body.
Depression and other emotional problems
Decreased memory and poor concentration (cognitive decline)
Who should pay particular attention to B12 supplementation?
The following four types of people are most deficient in vitamin B12
The first category is vegetarians
Especially for vegans who strictly abstain from eggs, dairy products, and any animal-based foods, vitamin B12 is primarily found in animal-based foods, making it easy for vegetarians to be deficient. Vitamin B12 is synthesized in the large intestine but absorbed at the end of the small intestine. Therefore, humans cannot obtain vitamin B12 from their own bodies and must obtain it from animal-based foods such as liver, kidneys, meat, fish, shellfish, poultry, eggs, and dairy products. This is why some vegetarians are deficient in vitamin B12.
The second category is the elderly
As people age, their bodies’ ability to absorb nutrients declines, and coupled with potential dietary restrictions, older adults are more prone to vitamin B12 deficiency.
The third category is patients with stomach problems
People with reduced stomach acid or those who take antacids for a long time are more susceptible to this condition because the absorption of vitamin B12 requires the assistance of stomach acid.
The fourth category is alcoholics
Long-term heavy drinking can interfere with the absorption and utilization of vitamin B12, leading to illness without the person realizing it.
Usage Guidelines: When and how to take it for best results?
- Food sources: Vitamin B12 is mainly found in animal-based foods, such as meat, fish, and dairy products. Vegetarians may need to obtain it through supplements or fortified foods, as plant-based foods generally do not contain vitamin B12.
- Reduce your intake of processed foods: Overly processed foods may destroy the vitamin B12 content. Choosing fresh, unprocessed foods is more conducive to getting enough B12.
Efficacy and Evidence: What are the proven benefits of B12 supplements?
Promotes red blood cell production: Vitamin B12 is essential for red blood cell production, participating in the synthesis of hemoglobin and helping to prevent anemia. Anemia can cause symptoms such as paleness, fatigue, and dizziness.
Maintaining Nervous System Health: Vitamin B12 is essential for the normal functioning of the nervous system, participating in the synthesis and repair of myelin sheaths and helping to maintain normal nerve conduction. Vitamin B12 deficiency may lead to neurological disorders such as memory loss and cognitive impairment.
Participation in DNA synthesis: Vitamin B12 plays a key role in DNA synthesis and is of great significance for cell proliferation and differentiation.
Promotes gut health: Vitamin B12 also plays an important role in maintaining gut health, promoting the growth and repair of intestinal cells and enhancing the intestinal barrier function.
Potential side effects and drug interactions of B12
Excessive vitamin B12 intake can have side effects. Vitamin B12 contains cobalt, which promotes the development and maturation of red blood cells, maintaining normal hematopoietic function and preventing pernicious anemia. However, excessive vitamin B12 intake can lead to allergic diseases, nerve damage, and worsen leukemia.
Conclusion
Vitamin B12, the only vitamin in the family containing a metallic element (cobalt), and the “little brother” among the B vitamins with the smallest requirement by the human body, plays an indispensable role. As an important coenzyme involved in many physiological functions of the human body, its deficiency can lead to many health problems and may also increase the risk of developing certain common chronic diseases.
